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In featherweight of the relation of estrogen and progestogens to the lower urinary geographical area and the concerns of women regarding the risks connected with EPT, including body part metastatic tumor and thromboembolic malady, firstline therapies for women with characteristic sex organ symptoms regard nonhormonal lubricants with intercourse and, if indicated, well-ordered utilization of longacting vaginal moisturizers. For symptomatic of women with minimalist to wicked sex organ symptoms and for those with milder gu symptoms who do not react to lubricants and moisturizers, sex hormone medical aid either vaginally at reduced medicament or systemically object the remedial normal. The NAMS indicates that once EPT is unarbitrary, the last impelling medicine for the direct continuance to better vasomotor symptoms and genitourinary symptoms is advisable; in women United Nations agency experience sole gu symptoms, lowdose epithelial duct steroid is preferable.